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If there is no open positions available in the group you would like to work in, do not hesitate to send unsolicited application directly to the group leader.
PhD position in Evolutionary Genomics of Adaptation at the University of Fribourg
A 4-yr PhD position in Evolutionary Genomics is available in the Flatt lab in the Department of Biology, University of Fribourg, Switzerland, to study the adaptive role of chromosomal inversions in fruit flies.
The PhD student will work on a project entitled "The Role of Chromosomal Inversions in Clinal Adaptation", recently funded by the SNSF and embedded in a designated project team consisting of three postdocs and a technician and supported by several international collaborations. Using an adaptive inversion polymorphism (a 'supergene') in Drosophila as a tractable model system, the aim of this project is to use genome sequencing, phenotypic assays, population cage experiments in the lab and field, population genetic modeling, genetic mapping (deficiency complementation mapping) and genome engineering (CRISPR/Cas9) to address how selection acts on inversions: (1) What are the genetic loci, i.e. the targets of selection, contained within the inversion? (2) How does the inversion and the candidate loci contained in it affect fitness-related traits? (3) What form of balancing selection (e.g., overdominance, frequency-dependent selection) maintains this adaptive inversion polymorphism?
The Department of Biology at the University of Fribourg is a highly dynamic, international and interdisciplinary environment, spanning a wide range of research in evolution and ecology, population genomics, and bioinformatics, developmental genetics, neurobiology, biochemistry and proteomics, across 27 groups. Research in our group is focused on understanding the genetic underpinnings of life-history adaptations, trade-offs between fitness traits, and the evolution of aging; more information on our lab
Candidates must be highly motivated and driven, have excellent oral and written communication skills, be able to work independently as well as in a team, and have a solid background or a strong interest in evolutionary genetics and a good working knowledge of statistics. Prior experience with Drosophila genetics and/or analyzing next generation sequencing data and/or population genetic modeling would be a plus. The working language is English. The starting date is flexible; the earliest start of the position would be January/February 2019. A master’s degree (or equivalent) is required to apply. The salary follows the doctoral salary rates set by the SNSF.
Please submit your application via email by 30 November 2018 to Prof. Thomas Flatt
Applicants must submit a single merged PDF file that includes a letter of motivation, a CV, names and contact details of two referees who should send their recommendation letter separately by email, and copies of their publications and/or their MSc thesis.
2 Funded PhD positions in theoretical ecology
Eco-evolutionary dynamics and, especially, the adaptive dynamics framework are major tools in linking the ecological dynamics of communities to species coevolution. In turn, coexistence theory studies the conditions enhancing the maintenance of biodiversity, while a central theory of ecosystem functioning is how the biodiversity relates to community productivity (the BEF relationship). The project aims at bridging eco-evolutionary dynamic to coexistence theory and BEF relationship. Specifically, we will extensively study the effects of coevolutionary trajectories on coexistence conditions and on ecosystem functioning. This will unravel the relationships imposed by ecoevolutionary dynamics between coexistence conditions and ecosystem functioning. In a second step, the project aims at disentangling the role coevolutionary dynamic from community dynamics in selecting specific network architecture. Once the emergence of specific systems is understood, we will study whether the architectures favouring species persistence under a pure community dynamics are also the ones favouring biodiversity once the co-evolutive process is added.
The ideal candidate is a very motivated student in ecology, with strong skills in theoretical ecology and background in modelling. The candidate should be familiar with at least one of the following topics:
eco-evolutionary dynamic, coexistence theory, or BEF relationship.
Available immediately, starting when possible, maximum 4 years. This position is funded by the Swiss National Science Foundation, and the salary matches their guidelines (gross salary starting at CHF 47’040 per year)
Applications (in French or in English), including a short cover letter (background and motivation), CV, and the name of one or two reference persons should be sent as a single attached pdf file to Rudolf Rohr
Dr. Rudolf P. Rohr
Department of Biology - Ecology and Evolution
University of Fribourg
Rohr group page
PhD and Postdoctoral Opportunities in Computational Biophysics and Biochemistry of Membranes
Several PhD and one postdoc positions are available in our newly-established Laboratory of Molecular Biophysics and Biochemistry.
Our group develops and applies computer simulations to investigate how the molecular properties of proteins, lipids and membranes modulate cellular processes. We combine these in silico investigations with biochemical and biophysical approaches to understand key biological mechanisms with atomistic molecular resolution. Please check our group webpage for more information.
Currently, we have openings in the following research areas:
- Intracellular lipid and fat accumulation
- Protein-membrane interactions
- Force field development
- Nanoparticles-membrane interactions
We are looking for highly motivated, team-oriented independent thinkers. For the postdoc position, the applicant should have a PhD in physics, chemistry, physical chemistry, biophysics, engineering or a related subject. The applicant should have a background in molecular dynamics simulations or computational chemistry. Previous experience in combining simulations with NMR experiments OR in simulations of materials/nanoparticles are a plus. For the PhD positions, the applicant should have a Master Degree in physics, chemistry, biology, bioinformatics, computer science, engineering or a related subject. Computer literacy and previous experience with molecular simulations, as well as good communication skills and proficiency in English are a plus. In general, any previous specific knowledge is less important than strong motivation, enthusiasm for scientific research, problem-solving skills, and possibly a track-record of individual and team accomplishments.
The positions are funded by the Swiss National Science Foundation and by the NCCR in Bio-Inspired Materials . We offer a stimulating, friendly and interdisciplinary work environment, with excellent working conditions (salary, resources, …) and frontier research projects. The Department of Biology of the University of Fribourg (Switzerland) gathers very dynamic researchers with a strong commitment toward innovation and excellence in science. It offers a stimulating and supportive environment, with an open-minded atmosphere ideal to foster synergies.
The selected candidates will also have the opportunity to interact extensively with members of the Department of Chemistry and of the Adolphe Merkle Institute in Fribourg, with whom collaborations are ongoing. In addition, they will also benefit from strong international collaborations with outstanding experimental labs in the fields of membrane biology, soft matter and nanomaterials. The successful PhD candidates will enrol in the Fribourg Graduate School of Life Sciences (FGLS) providing high-quality education opportunities to complement the laboratory training. It will also benefit from the close proximity to the CECAM headquarters in Lausanne, where multiple workshops and schools in computational science are held every year (https://www.cecam.org ). PhD positions are fully funded for 3 years, with a possible 1-year extension. In addition, PhD students will have the possibility to apply to generous international postdoctoral fellowship from the SNF after completion of their PhD. Initial gross annual salary for PhD students will be 47,040 CHF (~ 47,000 $). The postdoc position is fully funded for 2 years, with a possible 2-years extension. In addition, the postdoc will have the possibility to apply to prestigious and generous fellowships from the SNF to start an independent career after completion of their postdoctoral fellowship. Initial gross annual salary for Postdocs will be 65,000 CHF (~ 65,000 $).
Please send your application, including short cover letter (explaining background and motivation) and a complete CV via e-mail to Stefano Vanni.
Postdoc and PhD position available in the study of biogenesis of lipid droplets
We are looking for a postdoctoral researcher and a PhD student to study the biogenesis of lipid droplets using Baker's yeast as a genetic model organism. Techniques employed include live cell confocal microscopy, subcellular fractionation, and mass spectrometry. recent publication on the topic
We are looking for highly motivated candidates with an excellent background in cell biology. Additional experience in yeast genetics or lipid biochemistry would be an asset.
The positions are available immediately for the duration of at least 4-5 years. For further information please contact the group leader: Roger Schneiter