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PhD Position in Plant Signaling
Unraveling the role of CLE peptides in root growth and adaptations
A 4-yr PhD position in Plant signaling is available in the Hazak lab in the Department of Biology, University of Fribourg, Switzerland, to study the role of receptor-peptides-mediated pathways in Arabidopsis.
The PhD student will work on a project entitled "The Role of CLE peptides in root growth and adaptations", recently funded by the SNSF AMBIZIONE grant and supported by several international collaborations with three main objectives: (1) to investigate the role of CLE peptides in xylem formation; (2) to discover new CLE peptides-dependent pathways that act in plant adaptations to abiotic stresses; and (3) to develop new tools to tag and track the small CLE peptides in the plant tissues. A preliminary data is available for this project and two collaborators with complementary approaches will contribute to our research. This project will provide a substantial contribution to elucidating the role of these signaling molecules in plant growth and adaptations. The primary screen and molecular work will be done with the model plant Arabidopsis, but in the next step we will test the impact of our findings on crop species, like Tomato.
The Plant Signaling Group at the University of Fribourg is a new research team that examines both theoretical and applied questions in plant molecular physiology field using a combination of genetics, state-of the art confocal imaging and plant histology techniques. The overarching aim of the group is to further our understanding of the development of plant water conducting tissues called xylem, and to describe new molecular pathways involving CLE peptides and their receptors during plant adaptations to abiotic stresses. The Department of Biology at the University of Fribourg offers world-class facilities in a relaxing work atmosphere with lots of opportunities for collaboration. The Department of Biology is a highly dynamic, international and interdisciplinary, covering a wide range of research in plant molecular biology, ecology, bioinformatics, developmental genetics, neurobiology, biochemistry and proteomics, across 27 groups. For more information, contact the group leader Dr. Ora Hazak.
Candidates must be highly motivated and enthusiastic about the scientific research, have excellent oral and written communication skills, be able to work independently as well as in a team, and have a solid background or a strong interest in plant development and plant physiology. Prior experience with Arabidopsis genetics and phenotyping and confocal microscopy would be a plus. The working language is English. The starting date is flexible; the earliest start of the position would be March 2019. A master’s degree (or equivalent) is required to apply. The salary follows the doctoral salary rates set by the SNSF.
Please submit your application via email by 20 January 2019 to Dr. Ora Hazak
Applicants must submit a single merged PDF file that includes a letter of motivation, a CV, names and contact details of two referees who would send their recommendation letter separately by email, and copies of their publications and/or their MSc thesis.
2 Postdoc positions in Invasion Biology
The recently developed protocols EICAT and SEICAT allow classification of alien taxa according to the magnitude of their environmental and socio-economic impacts. EICAT has been recently adopted by the IUCN as a global standard for impacts of alien taxa (https://www.iucn.org/theme/species/our-work/invasive-species/eicat). However, although they allow adding a confidence score to each assessment, the consideration of this uncertainty in the final classification is currently inadequate. This leads to inconsistencies in impact assessments among assessors and might bias classifications for prioritizing alien species for management. Moreover, S/EICAT only consider detrimental impacts, but some aliens species also have beneficial impacts which are currently ignored.
Uncertainty in environmental and socio-economic impact assessments of alien taxa. Develop solutions for the treatment of uncertainty. The tasks of the postdoc will include: (1) Development of a publicly available database of alien species impacts that can be used for future assessments of all alien taxa; this database should be made available online and preferentially be hosted by a prominent international organization (e.g. IUCN). (2) S/EICAT assessments of European alien beetles as a model group, with the implementation of approaches for the treatment of uncertainty, and the analysis of these assessments to identify factors explaining context dependence in impact magnitudes.
Evaluating the positive and negative impacts of invasive species on biodiversity and ecosystem services. Adaptation of impact assessment protocols (S/EICAT) to consider not only detrimental but also the beneficial impacts of alien species on biodiversity and ecosystem services. Test the adaptation of S/EICAT on selected alien species across a wide range of taxa and habitats. This task will also compare the outputs of protocols applied at multiple scales (continental vs. local); and use different sources of information (literature review vs. empirical field data).
The University of Fribourg is a medium-sized Swiss university and provides a stimulating interdisciplinary work environment with a strong international orientation. Quality of life is very high in Fribourg, not the least due to its picturesque medieval town parts and proximity to the Alps. The Bacher lab (https://www3.unifr.ch/bio/en/groups/bacher) has an international reputation for high profile research on alien species, is globally well connected and was instrumental in the development of the S/EICAT protocols.
The ideal candidate holds an excellent PhD degree in ecology or related discipline. Previous experience with invasion science and database management is advantageous. S/he should have a deep interest in interdisciplinary collaboration. The scientific working language is English. Knowledge of spoken French or German would be advantageous to live in Fribourg, a bilingual town, but is not mandatory.
Entrance starting at earliest March 2019. The positions are initially limited to one year, but can be extended to 3 years. The positions are partly funded by the Swiss National Science Foundation and partly by the University of Fribourg. Gross salary depends on previous experience, but will be around CHF 70’000 per year.
A letter of motivation, CV, and contact information for two reference persons should be sent as a single attached pdf file to email@example.com by 10. December 2018.
Key Words: Alien species, impact assessments, beneficial and detrimental impacts, uncertainty, S/EICAT
Postdoctoral Fellow in Disease Proteomics and Protein Homeostasis
The Dengjel Lab at the Department of Biology, University of Fribourg is interested in skin biology and protein homeostasis. We characterize molecular pathways critical for wound healing and study
the function of small molecules to promote wound healing of chronic wounds. To study pathophysiological processes and the role of the cellular microenvironment in wound healing, we employ cell culture models, protein biochemistry and mass spectrometry-based proteomics.
We look for a postdoctoral fellow with expertise in the areas outlined above as demonstrated by first author papers and expect applicants to be motivated and interested in interdisciplinary research subjects. Excellent communication skills in English are of benefit.
- A stimulating, interdisciplinary scientific environment
- State-of-the-art central facilities for proteomics, imaging and bioinformatics analyses
- A two years postdoctoral position with competitive Swiss salary (CHF 80`000 per year), potentially extendable
The starting date for this position is earliest January 1st, 2019. Interested candidates should send a SINGLE PDF application including a CV, a brief statement of their research interests, a copy
of their PhD diploma, and names of three referees by email to firstname.lastname@example.org
PhD position in Evolutionary Genomics of Adaptation at the University of Fribourg
A 4-yr PhD position in Evolutionary Genomics is available in the Flatt lab in the Department of Biology, University of Fribourg, Switzerland, to study the adaptive role of chromosomal inversions in fruit flies.
The PhD student will work on a project entitled "The Role of Chromosomal Inversions in Clinal Adaptation", recently funded by the SNSF and embedded in a designated project team consisting of three postdocs and a technician and supported by several international collaborations. Using an adaptive inversion polymorphism (a 'supergene') in Drosophila as a tractable model system, the aim of this project is to use genome sequencing, phenotypic assays, population cage experiments in the lab and field, population genetic modeling, genetic mapping (deficiency complementation mapping) and genome engineering (CRISPR/Cas9) to address how selection acts on inversions: (1) What are the genetic loci, i.e. the targets of selection, contained within the inversion? (2) How does the inversion and the candidate loci contained in it affect fitness-related traits? (3) What form of balancing selection (e.g., overdominance, frequency-dependent selection) maintains this adaptive inversion polymorphism?
The Department of Biology at the University of Fribourg is a highly dynamic, international and interdisciplinary environment, spanning a wide range of research in evolution and ecology, population genomics, and bioinformatics, developmental genetics, neurobiology, biochemistry and proteomics, across 27 groups. Research in our group is focused on understanding the genetic underpinnings of life-history adaptations, trade-offs between fitness traits, and the evolution of aging; more information on our lab
Candidates must be highly motivated and driven, have excellent oral and written communication skills, be able to work independently as well as in a team, and have a solid background or a strong interest in evolutionary genetics and a good working knowledge of statistics. Prior experience with Drosophila genetics and/or analyzing next generation sequencing data and/or population genetic modeling would be a plus. The working language is English. The starting date is flexible; the earliest start of the position would be January/February 2019. A master’s degree (or equivalent) is required to apply. The salary follows the doctoral salary rates set by the SNSF.
Please submit your application via email by 30 November 2018 to Prof. Thomas Flatt
Applicants must submit a single merged PDF file that includes a letter of motivation, a CV, names and contact details of two referees who should send their recommendation letter separately by email, and copies of their publications and/or their MSc thesis.
2 Funded PhD positions in theoretical ecology
Eco-evolutionary dynamics and, especially, the adaptive dynamics framework are major tools in linking the ecological dynamics of communities to species coevolution. In turn, coexistence theory studies the conditions enhancing the maintenance of biodiversity, while a central theory of ecosystem functioning is how the biodiversity relates to community productivity (the BEF relationship). The project aims at bridging eco-evolutionary dynamic to coexistence theory and BEF relationship. Specifically, we will extensively study the effects of coevolutionary trajectories on coexistence conditions and on ecosystem functioning. This will unravel the relationships imposed by ecoevolutionary dynamics between coexistence conditions and ecosystem functioning. In a second step, the project aims at disentangling the role coevolutionary dynamic from community dynamics in selecting specific network architecture. Once the emergence of specific systems is understood, we will study whether the architectures favouring species persistence under a pure community dynamics are also the ones favouring biodiversity once the co-evolutive process is added.
The ideal candidate is a very motivated student in ecology, with strong skills in theoretical ecology and background in modelling. The candidate should be familiar with at least one of the following topics:
eco-evolutionary dynamic, coexistence theory, or BEF relationship.
Available immediately, starting when possible, maximum 4 years. This position is funded by the Swiss National Science Foundation, and the salary matches their guidelines (gross salary starting at CHF 47’040 per year)
Applications (in French or in English), including a short cover letter (background and motivation), CV, and the name of one or two reference persons should be sent as a single attached pdf file to Rudolf Rohr
Dr. Rudolf P. Rohr
Department of Biology - Ecology and Evolution
University of Fribourg
Rohr group page
PhD and Postdoctoral Opportunities in Computational Biophysics and Biochemistry of Membranes
Several PhD and one postdoc positions are available in our newly-established Laboratory of Molecular Biophysics and Biochemistry.
Our group develops and applies computer simulations to investigate how the molecular properties of proteins, lipids and membranes modulate cellular processes. We combine these in silico investigations with biochemical and biophysical approaches to understand key biological mechanisms with atomistic molecular resolution. Please check our group webpage for more information.
Currently, we have openings in the following research areas:
- Intracellular lipid and fat accumulation
- Protein-membrane interactions
- Force field development
- Nanoparticles-membrane interactions
We are looking for highly motivated, team-oriented independent thinkers. For the postdoc position, the applicant should have a PhD in physics, chemistry, physical chemistry, biophysics, engineering or a related subject. The applicant should have a background in molecular dynamics simulations or computational chemistry. Previous experience in combining simulations with NMR experiments OR in simulations of materials/nanoparticles are a plus. For the PhD positions, the applicant should have a Master Degree in physics, chemistry, biology, bioinformatics, computer science, engineering or a related subject. Computer literacy and previous experience with molecular simulations, as well as good communication skills and proficiency in English are a plus. In general, any previous specific knowledge is less important than strong motivation, enthusiasm for scientific research, problem-solving skills, and possibly a track-record of individual and team accomplishments.
The positions are funded by the Swiss National Science Foundation and by the NCCR in Bio-Inspired Materials . We offer a stimulating, friendly and interdisciplinary work environment, with excellent working conditions (salary, resources, …) and frontier research projects. The Department of Biology of the University of Fribourg (Switzerland) gathers very dynamic researchers with a strong commitment toward innovation and excellence in science. It offers a stimulating and supportive environment, with an open-minded atmosphere ideal to foster synergies.
The selected candidates will also have the opportunity to interact extensively with members of the Department of Chemistry and of the Adolphe Merkle Institute in Fribourg, with whom collaborations are ongoing. In addition, they will also benefit from strong international collaborations with outstanding experimental labs in the fields of membrane biology, soft matter and nanomaterials. The successful PhD candidates will enrol in the Fribourg Graduate School of Life Sciences (FGLS) providing high-quality education opportunities to complement the laboratory training. It will also benefit from the close proximity to the CECAM headquarters in Lausanne, where multiple workshops and schools in computational science are held every year (https://www.cecam.org ). PhD positions are fully funded for 3 years, with a possible 1-year extension. In addition, PhD students will have the possibility to apply to generous international postdoctoral fellowship from the SNF after completion of their PhD. Initial gross annual salary for PhD students will be 47,040 CHF (~ 47,000 $). The postdoc position is fully funded for 2 years, with a possible 2-years extension. In addition, the postdoc will have the possibility to apply to prestigious and generous fellowships from the SNF to start an independent career after completion of their postdoctoral fellowship. Initial gross annual salary for Postdocs will be 65,000 CHF (~ 65,000 $).
Please send your application, including short cover letter (explaining background and motivation) and a complete CV via e-mail to Stefano Vanni.
Postdoc and PhD position available in the study of biogenesis of lipid droplets
We are looking for a postdoctoral researcher and a PhD student to study the biogenesis of lipid droplets using Baker's yeast as a genetic model organism. Techniques employed include live cell confocal microscopy, subcellular fractionation, and mass spectrometry. recent publication on the topic
We are looking for highly motivated candidates with an excellent background in cell biology. Additional experience in yeast genetics or lipid biochemistry would be an asset.
The positions are available immediately for the duration of at least 4-5 years. For further information please contact the group leader: Roger Schneiter