Open Positions

Visit regularly this page to check out our open positions.
If there is no open positions available in the group you would like to work in, do not hesitate to send unsolicited application directly to the group leader. 

Jazwinska Lab

  • Post-doc Position: Cellular interactions during fin regeneration

    The zebrafish research group of Prof. Anna Jazwinska at the Department of Biology, University of Fribourg, Switzerland is looking for a motivated post-doctoral fellow with an interest in Regenerative Biology in Zebrafish.
    Among vertebrates, urodele amphibians and teleost fish display extraordinary regenerative potential. The zebrafish provides a unique vertebrate model system for regeneration studies due to its genetic amenability and simple maintenance. We do not understand why the regeneration response varies among adult vertebrates. Our goal is to uncover how the adult zebrafish and other fish species can naturally recreate a near-perfect replica of the lost complex tissue. Our specific aim is to identify the intrinsic genetic programs that support the regenerative plasticity of the regeneration-competent cells. This undertaking will demand the generation of transgenic fish lines, CRISPR/Cas9 system technology, pharmacological approaches, transcriptome analysis, and imaging techniques. A conceptual and molecular understanding of natural regeneration in lower vertebrates will help to build a foundation for regenerative medicine.

    Profile
    We are seeking highly motivated candidates with training in molecular and cell biology, preferentially with experience with zebrafish or other genetic model organisms. Suitable candidates should be enthusiastic about regenerative biology, have good knowledge of the English language, and at least some basic communication skills in either French or German. The candidate will have the opportunity to be part of a dynamic team and provide a meaningful contribution to the identification of biological mechanisms underlying organ regeneration in teleost fish.
    Financing: available

    The position is initially offered for one year with a trial period, with possible extension up to four years upon performance.

    Contact

    Email: Prof. Anna Jazwinska
    Lab web page

Stroeymeyt Lab

  • PhD position: Effects of pathogen pressure on personal and social immune investment in ants

    A 4-year PhD position is available in the research group of Professor Nathalie Stroeymeyt in the Department of Biology, University of Fribourg, to study the effect of prolonged pathogen pressure on long-term investment in personal and social immunity in ants.


    Background

    Group living offers favourable conditions for the spread of infectious diseases, because high population densities and frequent social contacts facilitate pathogen transmission. To mitigate that risk, social animals have evolved a variety of defence mechanisms to prevent the entry and propagation of pathogens within the group, ranging from a raised investment in personal immunity to highly coordinated collective sanitary actions (‘social immunity’). Recent studies have shown that social groups can also adopt organizational features, such as the subdivision into well-separated subgroups, which reduce epidemic risk through transmission bottleneck effects. However, the importance of organizational immunity features in disease risk management by real animal groups is still poorly understood. Our research adopts an empirical approach based on the experimental manipulations of garden ant colonies (Lasius niger) to (i) quantify the effect of social organization on disease transmission and test key predictions from network epidemiology, and (ii) evaluate the relative of importance of personal immunity, collective sanitary actions and organizational features under different environmental conditions and at different stages of development. More details

     

    The project
    The goal of this project will be to understand how ant colonies adjust different components of their disease defences (personal immunity, collective sanitary actions and transmission-inhibiting social organization) in response to repeated disease challenges. The candidate will use controlled pathogen inoculations, physiological assays and immune gene expression analysis, automated behavioural tracking, social network analysis and monitoring of the transmission of real agents to uncover the effect of prolonged pathogen pressure on long-term investment in personal and social immunity. The project will elucidate whether ants use changes in spatial and social organisation as an active strategy to decrease disease risk.


    Desired profile
    We are looking for candidates with experience in quantitative behavioural analysis and programming and/or molecular biology techniques, and a willingness to apply a variety of approaches (behavioural tracking, writing own code to analyse the data, and lab work). A good working knowledge in statistics and experimental design is also desirable. Experience with social insects and insect immunity would be a plus. Candidates must be creative, motivated and passionate about science, have excellent oral and written communication skills, and be at ease working both independently and as part of a team. A Master’s degree (or equivalent) will be required prior to taking up the position.


    The position
    The position will be part of an overall project team consisting of two PhD students and two post-doctoral researchers and will be fully funded for four years by an ERC Starting Grant. The salary will be set according to the guidelines of the University of Fribourg (c. 47’000 CHF per year).


    Location
    The Department of Biology at the University of Fribourg is a highly dynamic, international and interdisciplinary environment, spanning a wide range of research in evolution and ecology, behaviour, population genomics, and bioinformatics, developmental genetics, neurobiology, biochemistry and proteomics, across 27 groups.
    Expected starting date
    The starting date is flexible; the earliest possible start will be May 1st, 2019.


    How to apply
    Please send your application by email to Nathalie Stroeymeyt. Your application should consist of a single merged pdf file including: (i) a full CV and publication list, (ii) a 1-2 page research statement describing your main research interests and your relevant skillsets, how they developed, and how they relate to the proposed research project, (iii) the names and contact details of at least two referees, and (iv) copies of (or links to) your publications and/or your PhD thesis (if available). Evaluation of candidates will begin on February 15th, 2019, and continue until the position is filled.


    References
    Stroeymeyt et al. (2014). Organisational immunity in social insects. Current Opinion in Insect Science 5, 1.
    Stroeymeyt et al. (2018). Social network plasticity decreases disease transmission in a eusocial insect. Science 362, 941.

  • Post-doc position: Effects of caste-specific microbiota on disease susceptibility in ants

    A 3-year post-doc position is available in the research group of Professor Nathalie Stroeymeyt in the Department of Biology, University of Fribourg, to study the role of caste-specific microbiota in the disease defences of ant colonies.


    Background
    Group living offers favourable conditions for the spread of infectious diseases, because high population densities and frequent social contacts facilitate pathogen transmission. To mitigate that risk, social animals have evolved a variety of defence mechanisms to prevent the entry and propagation of pathogens within the group, ranging from a raised investment in personal immunity to highly coordinated collective sanitary actions (‘social immunity’). Recent studies have shown that social groups can also adopt organizational features, such as the subdivision into well-separated subgroups, which reduce epidemic risk through transmission bottleneck effects. However, the importance of organizational immunity features in disease risk management by real animal groups is still poorly understood. Our research adopts an empirical approach based on the experimental manipulations of garden ant colonies (Lasius niger) to (i) quantify the effect of social organization on disease transmission and test key predictions from network epidemiology, and (ii) evaluate the relative of importance of personal immunity, collective sanitary actions and organizational features under different environmental conditions and at different stages of development. More details 


    The project
    The goal of this project will be to study the role of caste-specific microbiota in the disease defences of ant colonies. The candidate will use DNA barcoding, gene expression analysis, physiological assays, microbiota manipulations and behavioural observations to (i) characterise the microbiota of ant workers depending on their caste, and (ii) test whether ants that perform risky tasks (e.g. foragers) have a microbiota which decreases their susceptibility to disease compared to ants that perform safe tasks (e.g. nurses), thus reducing the risk of epidemics at the colony-level. The candidate will also be involved in collaborations with other team members to characterise the immune response of ant workers to diverse fungal and bacterial pathogens.


    Desired profile
    We are looking for candidates with a strong background in molecular biology and/or microbiology, solid experience in lab work and analysis of sequencing data (e.g. DNA barcoding, quantification of gene expression), and a willingness to perform experiments involving live ants. A prior knowledge of insect immunity would be a plus. Candidates must be creative, motivated and passionate about science, have excellent oral and written communication skills, and be at ease working both independently and as part of a team. A PhD will be required prior to taking up the position.


    The position
    The position will be part of an overall project team consisting of two PhD students and two post-doctoral researchers and will be fully funded for three years by an ERC Starting Grant. The salary will be set according to the guidelines of the University of Fribourg (c. 75’000 CHF per year).


    Location
    The Department of Biology at the University of Fribourg is a highly dynamic, international and interdisciplinary environment, spanning a wide range of research in evolution and ecology, behaviour, population genomics, and bioinformatics, developmental genetics, neurobiology, biochemistry and proteomics, across 27 groups.


    Expected starting date
    The starting date is flexible; the earliest possible start will be May 1st, 2019.


    How to apply
    Please send your application by email to Nathalie.Stroeymeyt@gmail.com. Your application should consist of a single merged pdf file including: (i) a full CV and publication list, (ii) a 1-2 page research statement describing your main research interests and your relevant skillsets, how they developed, and how they relate to the proposed research project, (iii) the names and contact details of at least two referees, and (iv) copies of (or links to) your publications and/or your PhD thesis (if available). Evaluation of candidates will begin on February 15th, 2019, and continue until the position is filled.


    References
    Stroeymeyt et al. (2014). Organisational immunity in social insects. Current Opinion in Insect Science 5, 1.
    Stroeymeyt et al. (2018). Social network plasticity decreases disease transmission in a eusocial insect. Science 362, 941.

  • Post-doc position: Effects of social network structure on disease transmission in ants

    A 2-year post-doc position is available in the research group of Professor Nathalie Stroeymeyt in the Department of Biology, University of Fribourg, to study the effect of social network properties on disease transmission dynamics in ant colonies.


    Background
    Group living offers favourable conditions for the spread of infectious diseases, because high population densities and frequent social contacts facilitate pathogen transmission. To mitigate that risk, social animals have evolved a variety of defence mechanisms to prevent the entry and propagation of pathogens within the group, ranging from a raised investment in personal immunity to highly coordinated collective sanitary actions (‘social immunity’). Recent studies have shown that social groups can also adopt organizational features, such as the subdivision into well-separated subgroups, which reduce epidemic risk through transmission bottleneck effects. However, the importance of organizational immunity features in disease risk management by real animal groups is still poorly understood. Our research adopts an empirical approach based on the experimental manipulations of garden ant colonies (Lasius niger) to (i) quantify the effect of social organization on disease transmission and test key predictions from network epidemiology, and (ii) evaluate the relative of importance of personal immunity, collective sanitary actions and organizational features under different environmental conditions and at different stages of development. More details  

    The project
    The goal of this project will be to experimentally manipulate the social network topology of ant colonies (e.g. by manipulating nest architecture) to quantify the effect of network properties on disease transmission and test key predictions from network epidemiology. The candidate will use a combination of automated behavioural tracking, social network analysis, simulation of disease transmission, monitoring of the transmission of pathogenic and non-pathogenic agents, and fitness measurements to produce an integrative understanding of the effect of social organization and network structure on epidemic risk.


    Desired profile
    We are looking for candidates with a strong quantitative background and solid experience in programming, exploratory analysis of large biological datasets, social network analysis and/or epidemiological simulations. As the project will involve an important experimental component, the candidates would ideally have a good working knowledge of statistics and experimental design and prior experience with social insects. Experience with laser-cutting or 3D-printing software and tools would be a plus. Candidates must be creative, motivated and passionate about science, have excellent oral and written communication skills, and be at ease working both independently and as part of a team. A PhD will be required prior to taking up the position.


    The position
    The position will be part of an overall project team consisting of two PhD students and two post-doctoral researchers and will be fully funded for two years by an ERC Starting Grant. The salary will be set according to the guidelines of the University of Fribourg (c. 75’000 CHF per year).


    Location
    The Department of Biology at the University of Fribourg is a highly dynamic, international and interdisciplinary environment, spanning a wide range of research in evolution and ecology, behaviour, population genomics, and bioinformatics, developmental genetics, neurobiology, biochemistry and proteomics, across 27 groups.

    Expected starting date
    The starting date is flexible; the earliest possible start will be May 1st, 2019.


    How to apply
    Please send your application by email to Nathalie Stroeymeyt. Your application should consist of a single merged pdf file including: (i) a full CV and publication list, (ii) a 1-2 page research statement describing your main research interests and your relevant skillsets, how they developed, and how they relate to the proposed research project, (iii) the names and contact details of at least two referees, and (iv) copies of (or links to) your publications and/or your PhD thesis (if available). Evaluation of candidates will begin on February 15th, 2019, and continue until the position is filled.


    References
    Stroeymeyt et al. (2014). Organisational immunity in social insects. Current Opinion in Insect Science 5, 1.
    Stroeymeyt et al. (2018). Social network plasticity decreases disease transmission in a eusocial insect. Science 362, 941.

Dengjel Lab

  • Postdoctoral Fellow in Disease Proteomics and Protein Homeostasis

    The Dengjel Lab at the Department of Biology, University of Fribourg is interested in skin biology and protein homeostasis. We characterize molecular pathways critical for wound healing and study
    the function of small molecules to promote wound healing of chronic wounds. To study pathophysiological processes and the role of the cellular microenvironment in wound healing, we employ cell culture models, protein biochemistry and mass spectrometry-based proteomics.
    We look for a postdoctoral fellow with expertise in the areas outlined above as demonstrated by first author papers and expect applicants to be motivated and interested in interdisciplinary research subjects. Excellent communication skills in English are of benefit.


    We offer

    • A stimulating, interdisciplinary scientific environment
    • State-of-the-art central facilities for proteomics, imaging and bioinformatics analyses
    • A two years postdoctoral position with competitive Swiss salary (CHF 80`000 per year), potentially extendable

     

    The starting date for this position is earliest January 1st, 2019. Interested candidates should send a SINGLE PDF application including a CV, a brief statement of their research interests, a copy
    of their PhD diploma, and names of three referees by email to joern.dengjel@unifr.ch

Vanni Lab

  • PhD and Postdoctoral Opportunities in Computational Biophysics and Biochemistry of Membranes

    Several PhD and one postdoc positions are available in our newly-established Laboratory of Molecular Biophysics and Biochemistry.

    Your mission

    Our group develops and applies computer simulations to investigate how the molecular properties of proteins, lipids and membranes modulate cellular processes. We combine these in silico investigations with biochemical and biophysical approaches to understand key biological mechanisms with atomistic molecular resolution. Please check our group webpage for more information.

    Currently, we have openings in the following research areas:

    • Intracellular lipid and fat accumulation
    • Protein-membrane interactions
    • Force field development
    • Nanoparticles-membrane interactions

    Your profile

    We are looking for highly motivated, team-oriented independent thinkers. For the postdoc position, the applicant should have a PhD in physics, chemistry, physical chemistry, biophysics, engineering or a related subject. The applicant should have a background in molecular dynamics simulations or computational chemistry. Previous experience in combining simulations with NMR experiments OR in simulations of materials/nanoparticles are a plus. For the PhD positions, the applicant should have a Master Degree in physics, chemistry, biology, bioinformatics, computer science, engineering or a related subject. Computer literacy and previous experience with molecular simulations, as well as good communication skills and proficiency in English are a plus. In general, any previous specific knowledge is less important than strong motivation, enthusiasm for scientific research, problem-solving skills, and possibly a track-record of individual and team accomplishments.

    We offer

    The positions are funded by the Swiss National Science Foundation and by the NCCR in Bio-Inspired Materials . We offer a stimulating, friendly and interdisciplinary work environment, with excellent working conditions (salary, resources, …) and frontier research projects. The Department of Biology of the University of Fribourg (Switzerland) gathers very dynamic researchers with a strong commitment toward innovation and excellence in science. It offers a stimulating and supportive environment, with an open-minded atmosphere ideal to foster synergies.

    The selected candidates will also have the opportunity to interact extensively with members of the Department of Chemistry and of the Adolphe Merkle Institute in Fribourg, with whom collaborations are ongoing. In addition, they will also benefit from strong international collaborations with outstanding experimental labs in the fields of membrane biology, soft matter and nanomaterials. The successful PhD candidates will enrol in the Fribourg Graduate School of Life Sciences (FGLS) providing high-quality education opportunities to complement the laboratory training. It will also benefit from the close proximity to the CECAM headquarters in Lausanne, where multiple workshops and schools in computational science are held every year (https://www.cecam.org ). PhD positions are fully funded for 3 years, with a possible 1-year extension. In addition, PhD students will have the possibility to apply to generous international postdoctoral fellowship from the SNF after completion of their PhD. Initial gross annual salary for PhD students will be 47,040 CHF (~ 47,000 $). The postdoc position is fully funded for 2 years, with a possible 2-years extension. In addition, the postdoc will have the possibility to apply to prestigious and generous fellowships from the SNF to start an independent career after completion of their postdoctoral fellowship. Initial gross annual salary for Postdocs will be 65,000 CHF (~ 65,000 $).

     

    Please send your application, including short cover letter (explaining background and motivation) and a complete CV via e-mail to Stefano Vanni

     

Schneiter Lab

  • Postdoc and PhD position available in the study of biogenesis of lipid droplets

    Your mission

    We are looking for a postdoctoral researcher and a PhD student to study the biogenesis of lipid droplets using Baker's yeast as a genetic model organism. Techniques employed include live cell confocal microscopy, subcellular fractionation, and mass spectrometry. recent publication on the topic

    Your profile

    We are looking for highly motivated candidates with an excellent background in cell biology. Additional experience in yeast genetics or lipid biochemistry would be an asset.

    Starting date

    The positions are available immediately for the duration of at least 4-5 years. For further information please contact the group leader: Roger Schneiter