Christian Bochet Publications


Kastrati, A; Bochet, C.G.; "A Photochemical Amplifier Based on Self-Immolative Spacers"; J. Org. Chem. 2019 (in press).



Nkot, J.L.; Bikobo, D.S.N.; Zintchem, A.A.A.; Nyemeck, N.M.; Ndedi, E.D.M., Dihoue, P.H.B.; Pegnyemb, D.E.; Bochet, C.G.; Koert, U, "Antitubercular evaluation of root extract and isolated phytochemicals from Lophira lanceolata against two resistant strains of Mycobacterium tuberculosis"; Pharmaceutical Biology 2018, 56, 318-324.


Bielmann, A.; Sambiagio, N.; Wehr, N.; Gerber-Lemaire, S.; Bochet, C.G.; Curty, C., Synthesis of different Gluthathione-Sulfur Mustard Adducts of Verified and Potential Biomarkers. RSC Advances2018, 8, 23881-23890.


Remy, R.; Bochet, C.G. Application of Photoclick Chemistry for the Synthesis of Pyrazoles via 1,3-Dipolar Cycloaddition between Alkynes and Nitrilimines Generated in Situ, Eur. J. Org. Chem2018, 316-328.



Evina, J.N.; Bikobo, D.S.N.; Zintchem, A.A.A.; Nyemeck, N.M.; Ndedi, E.D.M., Dihoue, P.H.B.; Nyegue, M.A.; Atchade, A.D.; Pegnyemb, D.E.; Koert, U.; Bochet, C.G.  In vitro antitubercular activity of extract and constituents from the stem bark of Disthemonanthus benthamianus, Brazilian Journal of Pharmacognosy ,2017, 27, 793-743.

Bielmann, A.; Curty, C.; Bochet, C.G., Solid-phase Synthesis of the Aged-Nonapeptide-Nerve-Agent Adduct of Butyrylcholinesterase as Reference Materials for Analytical Verification, Helv. Chim. Acta, 2017, 100, e1700198.

Alimi, I.; Remy, R.; Bochet, C.G., Photochemical C-H activation: generation of indole and carbazole libraries, and first total synthesis of Clausenawalline D, Eur. J. Org. Chem. 2017, 3197-3210.

Nyemeck II, N. M.; Ngono Bikobo, D.S.; Zintchem, A.A.A.; Schäfer, E.M.; Bochet, C. G.; Pegnyemb, D. E.; Koert, U., A new procyanidin B from Campylospermum zenkeri (Ochnaceae) and antiplasmodial activity of two derivatives of (±)-serotobenine, Nat. Prod. Res2017, 1-10.

Balmer, D.; Bapst-Wicht, L.; Pyakurel, A.; Emery, M.; Nanchen, N.; Bochet, C.G.; Roduit, R., Bis-retinoid A2E Induces an Increase of basic Fibroblast Growth Factor via Inhibition of Extracellular signal-Regulated Kinases 1/2 Pathway in Retinal Pigment Epithelium Cells and Facilitates Phagocytosis, Front. Aging. Neurosci., 2017, 9(43), 1-12.



Chetioui, S.; Rouag, D.A.; Djukic, J.P.; Bochet, C.G.; Touzani, R.; Bailly, C.; Crochet, A.; Fromm, K.M., Crystal structures of a copper(II) and the isotypic nickel(II) and palladium(II) complexes of the ligand (E)-1-[(2,4,6-tribromophenyl)diazenyl]naphthalen-2-ol, Acta Cryst, Section E, 2016, 72(8), 1093-1098.

Remy, R.; Bochet, C.G. The Arene-Alkene Cycloaddition, Chem. Rev., 2016, 116, 9816-9849.

Dennison, G.H.; Bochet, C.G.; Curty, C.; Ducry, J.; Nielsen, D.J.; Sambrook, M.R.; Zaugg, A.; Johnston, M. R., Supramolecular Agent-Simulant Correlations for the Luminescence Based Detection of V-Series Chemical Warfare Agents with Trivalent Lanthanide Complexes, Eur. J. Inorg. Chem. 2016, 9, 1348-1358.


C.G. Bochet, Probing mechanisms of photochemical reactions: how to teach a young dog old tricks, Chimia, 2016, 70, 182-185.



Janett, E.; Bernardinelli, Y.; Müller, D.; Bochet, C.G. Synthesis of FMRFaNV, a photoreleasable caged transmitter designed to study neurons-glia interactions in the central nervous system, Bioconjugate Chemistry, 2015, 26, 2408-2418.

Chetioui, S.; Hamdouni, N.; Bochet, C G.; Djukic, J.P.; Bailly, C., Crystal structure of bis{?-1-[(E)-(3-methoxyphenyl)diazenyl]naphthalen-2-olato-?3N2,O:O}bis({1-[(E)-(3-methoxyphenyl)diazenyl]naphthalen-2-olato-?2N2,O}copper(II)), Acta Cryst, Section E, 2015, 71(12), 211-212.

Anstaett, P.; Leonidova, A.; Janett, E.; Bochet, C. G.; Gasser, G., Reply to the Commentary by Trentham et al. on “Caged Phosphate and the Slips and Misses in Determination of Quantum Yields for Ultraviolet-A-Induced Photouncaging” by Gasser and Co-Workers, ChemPhysChem, 2015, 16, 1863-1866.

Ndongo, J. T.; Issa, M. E; Messi, A. N.; Ngo Mbing, J.; Cuendet, M.; Pegnyemb, D. E.; Bochet, C. G.; Cytotoxic flavonoid and other constituents from the stem bark of Ochna schweinfurthianaNat. Prod. Res., 2015, 29(17), 1684-1687.



Bernardinelli, Y.; Randall, J.; Janett, E.; Nikonenko, I.; König, S.; Jones, E. V.; Flores, C. E.; Murai, K. K.; Bochet, C. G.; Holtmaat, A.; Muller, D., Activity-Dependent Structural Plasticity of Perisynaptic Astrocytic Domains Promotes Excitatory Synapse Stability, Current Biology 2014, 24(15), 1679-1688.

Zimmermann, M.; Cal, R.; Janett, E.; Hoffmann, V.; Bochet, C. G.; Constable, E.; Beaufils, F.; Wymann, M. P. Angew. Chem. Int. Ed., 2014, 53, 4717–4720.

T. Solomek, C.G. Bochet, T. Bally, The Primary Steps in Excited State Hydrogen Transfer: The Phototautomerization of o-Nitrobenzyl Derivatives, Chem. Eur. J. 2014, 20, 8062-8067.



C.G. Bochet, Towards a photochemical synthesis of peptides, Chimia, 2013, 67, 896-898.

U. Streit, F. Birbaum, A. Quattropani, CG. Bochet, The photocycloaddition of arenes and allenes, J. Org. Chem. 2013, 78, 6890-6910.

A. Crochet, I. Alimi, C.G. Bochet, K.M. Fromm, Acta Crystallographica Sect. E, 2013, E69, o339.


Klan, P.; Solomek, T.; Bochet, C. G.; Blanc, A.; Givens, R.; Rubina, M.; Popik, V.; Kostikov, A.; Wirz, J. Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and Efficacy, Chem. Rev., 2013, 113, 119-191.



T. Solomek, S. Mercier, T. Bally, C.G. Bochet, Photolysis of ortho-nitrobenzylic derivatives: the importance of the leaving group, Photochem. Photobiol. Sci., 2012,11, 548-555. 


J.L. Débieux, C.G. Bochet, The all-photochemical synthesis of an OGP(10-14) precursor, Chem. Sci., 2012, 3, 405-406. 



C.G. Bochet, A. Blanc, Photolabile protecting groups in organic synthesis, in 2010 CRC Handbook of photochemistry and photobiology, A. Griesbeck, M. Oelgemoeller, Eds, Taylor and Francis 2011.


N. Charbonnet, E. Riguet, C. G. Bochet, Singlet oxygen-induced rearrangement of furan derivatives, Synlett, 2011, 2231-2233.

V. San Miguel Arnanz, C. G. Bochet, A. del Campo, Wavelength selective caged surfaces: how many functional levels are possible? J. Am. Chem. Soc2011, 133, 5380-5388.

U. Streit, C. G. Bochet, The arene-alkene photocycloaddition, Beilstein Journal of Organic Chemistry, 2011, 7, 525-542.


H. Haning, C.G. Mañas, V. Paddock, C.G. Bochet, A.J.P. White, G. Bernardinelli, I. Mann, W. Oppolzer, A.C. Spivey, Total Synthesis of the Amaryllicaceae Alkaloid Clivonine, Org. Biomol. Chem2011, 9, 2809-2820.


T. Jack, J. Simonin, S. Singhanat, C. G. Bochet, “Unconventional Methods in Organic Synthesis”, 41th CUSO Summer School in Organic Chemistry. Chimia, 2011,65, 97-99.



C.G. Mañas, V. Paddock, C.G. Bochet, A.C. Spivey, A.J.P. White, I. Mann, W. Oppolzer, Total Synthesis of the Lycorenine-type Amaryllicaceae Alkaloid (+/-)-Clivonine via a Biomimetic Ring-switch from a Lycorine-type Progenitor, J. Am. Chem. Soc., 2010, 132, 5176-5178.


J.L. Débieux, C.G. Bochet, Photoinduced acyl transfer, J. Phys. Org. Chem. 2010, 23, 272-282. 



C.G. Bochet, Hard work and light experience: early steps in photochemistry, Chimia2009, 63, 872-874 


C.G. Bochet, T. Draper, B. Bocquet, M.T. Pope, A.F. Williams, 182Tungsten Mössbauer spectroscopy of heteropolytungstates, Dalton Trans., 2009, 5127-5131.


J.L. Débieux, C.G. Bochet, Preparation of photoactivable amino acid derivatives, J. Org. Chem., 2009, 74, 4519-4524.

C.G. Bochet, A. Blanc, Photolabile protecting groups in organic synthesis, in Handbook of preparative photochemistry, Angelo Albini, Ed., John Wiley 2009, in press.

F.L. Stefanato, E. Abou-Mansour, A. Buchala, M. Kretschmer, A. Mosbach, M. Hahn, C.G. Bochet, J-P. Métraux, H.J. Schoonbeek, The ABC-transporter BcatrB protects Botrytis cinerea against camalexin and is a virulence factor on Arabidopsis thaliana, The Plant Journal, 2009, 58(3), 499-510.


S. Mercier, C.G. Bochet, Photolabile linkers units, in Linker Strategies in Solid-Phase Organic Synthesis, Peter Scott, Ed., John Wiley 2009.



U. Streit, C.G. Bochet, Recent advances in arene photocycloadditions, Chimia 2008,62, 962-966.

F. Birbaum, A. Neels, C.G. Bochet, The photochemistry of allenyl salicylaldehydes, Org. Lett. 2008, 10, 3175-3178. 


J. Haesler, I. Schindelholz, E. Riguet, C.G. Bochet, W. Hug, Absolute Configuration of Chirally Deuterated Neopentane, Nature 2007446 , 526-529. 


E. Riguet, C.G. Bochet, A new safety-catch photolabile protecting group, Org. Lett. 2007 , 5453-5456. 

C.-L. Ciana, C.G. Bochet, Clean and Easy Photochemistry, Chimia 2007, 650-654

J.L. Débieux, A. Cosandey, C. Helgen, C.G. Bochet, Photoacylation of alcohols in neutral medium, Eur. J. Org. Chem. 20072073-2077. 


A. Blanc, C.G. Bochet, Isotope Effects in Photochemistry. 2. Application to Chromatic Orthogonality , Organic Letters, 2007, 2649-2651. 


C. Helgen, C.G. Bochet, Photoacylation of amines with new heterocycles, Heterocycles2006 67(2) , 797-805. 

C.G. Bochet, Photochemical release of various functional groups, Pure & Appl. Chem., 2006 78(2) , 241-247. 



J. Lage Robles, C.G. Bochet, Photochemical liberation of aldehydes, Org. Lett2005, , 3545-3547. 

A.D. Cohen, C. Helgen, C.G. Bochet, J.P. Toscano, The Mechanism of Photoinduced Acylation of Amines by N-Acyl-5,7-dinitroindoline as Determined by TRIR Spectroscopy, Org. Lett. 2005 , 2845-2847. 

V. Tamilmani, C.A. Daul, J. Lage Robles, C.G. Bochet, P. Venuvanalingam, Hydrogen Bond Stabilization in Diels-Alder Transition States. The Cycloaddition of hydroxy-ortho-quinodimethane with Fumaric acid and Dimethylfumarate. Chem. Phys. Lett2005 406 , 355-359 


C.G. Bochet, Photochemical activation of functional groups, in Advances in Organic SynthesisG. Jenner, Ed., 2005 , 3-23. 


V. Fluxa, T.A. Jenny, C.G. Bochet, Determination of tetrasubstituted alkene geometry by proton NMR, Tetrahedron Lett2005 46 , 3793-3795.



C.G. Bochet, Chromatic orthogonality in organic synthesis, Synlett 2004 2268-2274. 


A. Blanc, C.G. Bochet, Isotope Effects in Photochemistry. 1. -Nitrobenzyl alcohol derivatives, J. Am. Chem. Soc., 2004 126 , 7174-7175. 


M. Kessler, R. Glatthar, B. Giese, C.G. Bochet, Orthogonal Photocleavable Protecting Groups in Solid Phase Synthesis, Org. Lett. 2003 , 1179-1181. 
A. Blanc, C.G. Bochet, Bis-(o-nitrophenyl)-ethanediol: a practical photolabile protecting group for ketones and aldehydes, J. Org. Chem2003 68 , 1138-1141. 


K.M. Fromm, E.D. Gueneau, H. Goesmann, C.G. Bochet, One-dimensional water" and "one-dimensional acid" as new proton conducting material in analogy to biological water channels? Synthesis and the unique crystal structure of 1 ? [(H 2 O) Ì (DB18C6)( m 2 -H 2 O) 2/2 ] 1 ? [(H 3 O) Ì (DB18C6)( m 2 -H 2 O) 2/2 ]I 3 (DB18C6 = dibenzo-18-crown-6), Z. Anorg. Allg. Chem2003 ,629 , 597-600 

C. Helgen, C.G. Bochet, Photochemical Protection of Amines with the Cbz Group, J. Org. Chem2003 68 , 2483-2486 


A. Blanc, C.G. Bochet, Wavelength-controlled orthogonal photolysis of protecting groups, J. Org. Chem2002 67 , 5567-5577. 


C.G. Bochet, Photolabile protecting groups and linkers, J. Chem. Soc.Perkin Trans. I 2002 , 125-152.



C. Helgen, C.G. Bochet, Preparation of Secondary and Tertiary Amides under Neutral Conditions by Photochemical Acylation of Amines, Synlett 2001, 1968-1970. 


C.G. Bochet, Selective Synthesis, New Reagents for Specific Transformations, Champéry, June 6-9, 2001, Chimia 2001, 55, 732-736 

C.G. Bochet, Orthogonal Photolysis of Protecting Groups. Angew. Chem. Int. Ed. Engl2001 40 , 2071-2073. 

D. D'Addona, C.G. Bochet, Preparation of carbamates from alcohols and amines under mild conditions, Tetrahedron Lett. 2001 42, 5227-5229. 


C.G. Bochet, Wavelength-selective Cleavage of Photolabile Protecting Groups. Tetrahedron Lett2000 41 , 6341-6346. 

W. Oppolzer, C.G. Bochet, Asymmetric synthesis of the spirocyclic core of the Cylindricine-type alkaloids. Tetrahedron: Asymmetry 2000 11 , 4761-4770. 


C. Edder, C. Piguet, G. Bernardinelli, J. Mareda, C.G. Bochet, J.C.G. Bünzli, G. Hopfgartner, Control of Thermodynamic Selectivity and Fine Tuning of Iron(II) Spin-crossover Equilibria in Self-assembled Non-covalent Heterodimetallic d-f Podates: Unusual Electronic Effects of Electro-withdrawing Sulfonamide Groups. Inorg. Chem2000 39 , 5059-5073 

C. G. Bochet, 35th ESF/EUCHEM Conference on Stereochemistry, Chimia 2000 54, 472-477. 



B.M. Trost, T.L. Calkins, C.G. Bochet, A concise convergent synthesis of (+)-Parviflorin, (+)-Squamocin K and (+)-5 -hydroxyparviflorin. Angew. Chem. Int. Ed.Engl. 1997, 36, 2632-2635. 



C.G. Bochet, Synthèse asymétrique d'alcaloïdes par hydroxyamination électrophile d'énolates chiraux. Première synthèse totale de la (+)-Trianthine. Université de Genève, Thèse N° 28361996. 


W. Oppolzer, C.G. Bochet, Enantioselective Preparation and Hydroboration of Cyclic Enamides: Synthesis of (2S)-Pseudoconhydrine, Tetrahedron Lett., 1995, 36, 2959-2962. 


C. Piguet, J.C.G. Bünzli, G. Bernardinelli, C.G. Bochet, P. Froidevaux, Design of Luminescent Building Blocks for Supramolecular Triple-Helical Lanthanide Complexes, J. Chem. Soc., Dalton Trans1995, 83-97. 


W. Oppolzer, C.G. Bochet, E. Merifield, Diastereo- and Enantioselective Syntheses of (-)-Coniine, (-)-Solenopsin A, (-)-Solenopsis fugax venom and (-)-Xenovenine via Deoxygenative Decarboxylation of 2-Carbonylsultam-Substituted N-Hydroxy-Piperidines and Pyrrolidines, Tetrahedron Letters 1994, 35, 7015-7018. 


W. Oppolzer, A.C. Spivey, C.G. Bochet, Suprafaciality of Thermal -4-Alkenylhydroxylamine Cyclizations: Syntheses of (±)- a -Lycorane and (+)-Trianthine, J. Am. Chem. Soc.,1994, 116, 3139-3140. 


C.G. Bochet, C. Piguet, A.F. Williams, Synthesis and Electronic Properties of Intensely Coloured Iron(II) Complexes with New 4-Substituted Planar Tridentate Nitrogen Ligands Analogous to 2,2':6',2"-Terpyridine, Helv. Chim. Acta, 1993 76 , 372-384.