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My main interest is the understanding of the neural control of movement with a focus on translational applications in motor disorders. My background in applied physics has strongly influenced my path since the beginning. Indeed, when I started my PhD program in Biomedical Engineering as a fellow of the Scuola Superiore Sant'Anna, in Pisa, I was looking neither for a purely theoretical research program nor purely experimental. My intention was to understand the basic interactions between neuromodulation technologies and sensorimotor circuit dynamics. I wanted to develop theoretical tools to support translation and bring them all the way down to the clinics to test whether my findings and ideas had any impact at all on actual clinical applications. After a PhD and a 3-yr post-doc program under the supervision of Prof. Silvestro Micera first and Prof. Gregoire Courtine later I am deeply convinced that a theoretical approach to translational neuroscience can have a significant impact on clinical applications. Indeed I have used computational models to design and implement real-time neurotechnologies that I have tested in rats, non-human primates and humans. I have started with simple models of the peripheral nerve that I have slowly improved to complex neuro-biomechanical models of the spinal sensorimotor circuits, while at the same time performing animal experiments to test my models up to the implementation of real-time technologies able to restore sensation in human amputees and brain-controlled locomotion in non-human primates after spinal cord injury. Ultimately, I love science.